Crystallization and X-ray data analysis of the 10 kDa C-terminal lid subdomain from Caenorhabditis elegans Hsp70

Por Worrall, Liam, Walkinshaw, Malcolm D.
Publicado em 2006

Streamlined, automated protocols for the production of milligram quantities of untagged recombinant human cyclophilin-A (hCypA) and untagged human proliferating cell nuclear antige...

Por Ludwig, Cornelia, Wear, Martin A., Walkinshaw, Malcolm D.
Publicado em 2010

Crystallization of a Mos1 transposase–inverted-repeat DNA complex: biochemical and preliminary crystallographic analyses

Por Richardson, Julia M., Finnegan, David J., Walkinshaw, Malcolm D.
Publicado em 2007

A Molecular Dynamics Study of Allosteric Transitions in Leishmania mexicana Pyruvate Kinase

Por Naithani, Ankita, Taylor, Paul, Erman, Burak, Walkinshaw, Malcolm D.
Publicado no Biophys J (2015)

Structure- and Ligand-Based Virtual Screening Identifies New Scaffolds for Inhibitors of the Oncoprotein MDM2

Por Houston, Douglas R., Yen, Li-Hsuan, Pettit, Simon, Walkinshaw, Malcolm D.
Publicado no PLoS One (2015)

Molecular architecture of the Mos1 paired-end complex: the structural basis of DNA transposition in a eukaryote

Por Richardson, Julia M., Colloms, Sean D., Finnegan, David J., Walkinshaw, Malcolm D.
Publicado em 2009

Crystallization and X-ray analysis of the T = 4 particle of hepatitis B capsid protein with an N-­terminal extension

Por Tan, Wen Siang, McNae, Iain W., Ho, Kok Lian, Walkinshaw, Malcolm D.
Publicado em 2007

Crystal structure of dihydrofolate reductase from Plasmodium vivax: Pyrimethamine displacement linked with mutation-induced resistance

Por Kongsaeree, Palangpon, Khongsuk, Puttapol, Leartsakulpanich, Ubolsree, Chitnumsub, Penchit, Tarnchompoo, Bongkoch, Walkinshaw, Malcolm D., Yuthavong, Yongyuth
Publicado em 2005

Crystallization and X-ray structure of cold-shock protein E from Salmonella typhimurium

Por Morgan, Hugh P., Wear, Martin A., McNae, Iain, Gallagher, Maurice P., Walkinshaw, Malcolm D.
Publicado em 2009

Mechanism of Mos1 transposition: insights from structural analysis

Por Richardson, Julia M, Dawson, Angela, O'hagan, Natasha, Taylor, Paul, Finnegan, David J, Walkinshaw, Malcolm D
Publicado em 2006

Thermo‐kinetic analysis space expansion for cyclophilin‐ligand interactions – identification of a new nonpeptide inhibitor using Biacore™ T200

Por Wear, Martin A., Nowicki, Matthew W., Blackburn, Elizabeth A., McNae, Iain W., Walkinshaw, Malcolm D.
Publicado no FEBS Open Bio (2017)

A Novel p53 Phosphorylation Site within the MDM2 Ubiquitination Signal: II. A MODEL IN WHICH PHOSPHORYLATION AT SER(269) INDUCES A MUTANT CONFORMATION TO p53

Por Fraser, Jennifer A., Madhumalar, Arumugam, Blackburn, Elizabeth, Bramham, Janice, Walkinshaw, Malcolm D., Verma, Chandra, Hupp, Ted R.
Publicado em 2010

EDULISS: a small-molecule database with data-mining and pharmacophore searching capabilities

Por Hsin, Kun-Yi, Morgan, Hugh P., Shave, Steven R., Hinton, Andrew C., Taylor, Paul, Walkinshaw, Malcolm D.
Publicado em 2011

Protein recognition of macrocycles: Binding of anti-HIV metallocyclams to lysozyme

Por Hunter, Tina M., McNae, Iain W., Liang, Xiangyang, Bella, Juraj, Parsons, Simon, Walkinshaw, Malcolm D., Sadler, Peter J.
Publicado em 2005

STRUCTURAL CHARACTERISATION OF THE LEISHMANIA MAJOR ORTHOLOGUES OF MACROPHAGE MIGRATION INHIBITORY FACTOR (MIF)

Por Richardson, Julia M., Morrison, Lesley S., Bland, Nicholas D., Bruce, Sandra, Coombs, Graham H., Mottram, Jeremy C., Walkinshaw, Malcolm D.
Publicado em 2009

Identification and activity of inhibitors of the essential nematode-specific metalloprotease DPY-31

Por France, David J., Stepek, Gillian, Houston, Douglas R., Williams, Lewis, McCormack, Gillian, Walkinshaw, Malcolm D., Page, Antony P.
Publicado no Bioorg Med Chem Lett (2015)

UFSRAT: Ultra-Fast Shape Recognition with Atom Types –The Discovery of Novel Bioactive Small Molecular Scaffolds for FKBP12 and 11βHSD1

Por Shave, Steven, Blackburn, Elizabeth A., Adie, Jillian, Houston, Douglas R., Auer, Manfred, Webster, Scott P., Taylor, Paul, Walkinshaw, Malcolm D.
Publicado no PLoS One (2015)

Structures of pyruvate kinases display evolutionarily divergent allosteric strategies

Por Morgan, Hugh P., Zhong, Wenhe, McNae, Iain W., Michels, Paul A. M., Fothergill-Gilmore, Linda A., Walkinshaw, Malcolm D.
Publicado no R Soc Open Sci (2014)

Cyclophilin40 isomerase activity is regulated by a temperature-dependent allosteric interaction with Hsp90

Por Blackburn, Elizabeth A., Wear, Martin A., Landré, Vivian, Narayan, Vikram, Ning, Jia, Erman, Burak, Ball, Kathryn L., Walkinshaw, Malcolm D.
Publicado no Biosci Rep (2015)

An improved strategy for the crystallization of Leishmania mexicana pyruvate kinase

Por Morgan, Hugh P., McNae, Iain W., Hsin, Kun-Yi, Michels, Paul A. M., Fothergill-Gilmore, Linda A., Walkinshaw, Malcolm D.
Publicado em 2010