Crystallization and X-ray structure of cold-shock protein E from Salmonella typhimurium

Por Morgan, Hugh P., Wear, Martin A., McNae, Iain, Gallagher, Maurice P., Walkinshaw, Malcolm D.
Publicado em 2009

EDULISS: a small-molecule database with data-mining and pharmacophore searching capabilities

Por Hsin, Kun-Yi, Morgan, Hugh P., Shave, Steven R., Hinton, Andrew C., Taylor, Paul, Walkinshaw, Malcolm D.
Publicado em 2011

Structures of pyruvate kinases display evolutionarily divergent allosteric strategies

Por Morgan, Hugh P., Zhong, Wenhe, McNae, Iain W., Michels, Paul A. M., Fothergill-Gilmore, Linda A., Walkinshaw, Malcolm D.
Publicado no R Soc Open Sci (2014)

An improved strategy for the crystallization of Leishmania mexicana pyruvate kinase

Por Morgan, Hugh P., McNae, Iain W., Hsin, Kun-Yi, Michels, Paul A. M., Fothergill-Gilmore, Linda A., Walkinshaw, Malcolm D.
Publicado em 2010

Allosteric Mechanism of Pyruvate Kinase from Leishmania mexicana Uses a Rock and Lock Model

Por Morgan, Hugh P., McNae, Iain W., Nowicki, Matthew W., Hannaert, Véronique, Michels, Paul A. M., Fothergill-Gilmore, Linda A., Walkinshaw, Malcolm D.
Publicado em 2010

M2 pyruvate kinase provides a mechanism for nutrient sensing and regulation of cell proliferation

Por Morgan, Hugh P., O’Reilly, Francis J., Wear, Martin A., O’Neill, J. Robert, Fothergill-Gilmore, Linda A., Hupp, Ted, Walkinshaw, Malcolm D.
Publicado em 2013

Sequence specificity of single-stranded DNA-binding proteins: a novel DNA microarray approach

Por Morgan, Hugh P., Estibeiro, Peter, Wear, Martin A., Max, Klaas E.A., Heinemann, Udo, Cubeddu, Liza, Gallagher, Maurice P., Sadler, Peter J., Walkinshaw, Malcolm D.
Publicado em 2007

The Trypanocidal Drug Suramin and Other Trypan Blue Mimetics Are Inhibitors of Pyruvate Kinases and Bind to the Adenosine Site

Por Morgan, Hugh P., McNae, Iain W., Nowicki, Matthew W., Zhong, Wenhe, Michels, Paul A. M., Auld, Douglas S., Fothergill-Gilmore, Linda A., Walkinshaw, Malcolm D.
Publicado em 2011

Structural Analysis of the C-Terminal Region (Modules 18–20) of Complement Regulator Factor H (FH)

Por Morgan, Hugh P., Mertens, Haydyn D. T., Guariento, Mara, Schmidt, Christoph Q., Soares, Dinesh C., Svergun, Dmitri I., Herbert, Andrew P., Barlow, Paul N., Hannan, Jonathan P.
Publicado em 2012

Structural basis for engagement by complement factor H of C3b on a self surface

Por Morgan, Hugh P., Schmidt, Christoph Q., Guariento, Mara, Blaum, Bärbel S., Gillespie, Dominic, Herbert, Andrew P., Kavanagh, David, Mertens, Haydyn D. T., Svergun, Dmitri I., Johansson, Conny M., Uhrín, Dušan, Barlow, Paul N., Hannan, Jonathan P.
Publicado em 2011

A new family of covalent inhibitors block nucleotide binding to the active site of pyruvate kinase

Por Morgan, Hugh P., Walsh, Martin J., Blackburn, Elizabeth A., Wear, Martin A., Boxer, Matthew B., Shen, Min, Mcnae, Iain W., Nowicki, Matthew W., Michels, Paul A. M., Auld, Douglas S., Fothergill-Gilmore, Linda A., Walkinshaw, Malcolm D.
Publicado em 2012

Identification of ML251, a Potent Inhibitor of T. brucei and T. cruzi Phosphofructokinase

Por Brimacombe, Kyle R., Walsh, Martin J., Liu, Li, Vásquez-Valdivieso, Montserrat G., Morgan, Hugh P., McNae, Iain, Fothergill-Gilmore, Linda A., Michels, Paul A. M., Auld, Douglas S., Simeonov, Anton, Walkinshaw, Malcolm D., Shen, Min, Boxer, Matthew B.
Publicado em 2013