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Allosteric Mechanism of Pyruvate Kinase from Leishmania mexicana Uses a Rock and Lock Model
Allosteric regulation provides a rate management system for enzymes involved in many cellular processes. Ligand-controlled regulation is easily recognizable, but the underlying molecular mechanisms have remained elusive. We have obtained the first complete series of allosteric structures, in all pos...
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| Autores principales: | , , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
American Society for Biochemistry and Molecular Biology
2010
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2857090/ https://ncbi.nlm.nih.gov/pubmed/20123988 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.079905 |
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