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A Molecular Dynamics Study of Allosteric Transitions in Leishmania mexicana Pyruvate Kinase
A comparative molecular dynamics analysis of the pyruvate kinase from Leishmania mexicana is presented in the absence and presence of the allosteric effector fructose 2,6-bisphosphate. Comparisons of the simulations of the large 240 kDa apo and holo tetramers show that binding of fructose 2,6-bispho...
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| Publicado no: | Biophys J |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Biophysical Society
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4576150/ https://ncbi.nlm.nih.gov/pubmed/26210208 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2015.05.040 |
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