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Cheminformatic models based on machine learning for pyruvate kinase inhibitors of Leishmania mexicana

BACKGROUND: Leishmaniasis is a neglected tropical disease which affects approx. 12 million individuals worldwide and caused by parasite Leishmania. The current drugs used in the treatment of Leishmaniasis are highly toxic and has seen widespread emergence of drug resistant strains which necessitates...

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Publicado en:BMC Bioinformatics
Main Authors: Jamal, Salma, Scaria, Vinod
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2013
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4225525/
https://ncbi.nlm.nih.gov/pubmed/24252103
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-14-329
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