Structural basis for engagement by complement factor H of C3b on a self surface

Complement factor H (FH) attenuates C3b molecules tethered via their thioester domains to self-surfaces and thereby protects host tissues. FH is a cofactor for initial C3b proteolysis that ultimately yields a surface-attached fragment (C3d), corresponding to the thioester domain. We used NMR and X-r...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
Main Authors: Morgan, Hugh P., Schmidt, Christoph Q., Guariento, Mara, Blaum, Bärbel S., Gillespie, Dominic, Herbert, Andrew P., Kavanagh, David, Mertens, Haydyn D. T., Svergun, Dmitri I., Johansson, Conny M., Uhrín, Dušan, Barlow, Paul N., Hannan, Jonathan P.
Format: Artigo
Jezik:Inglês
Izdano: 2011
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3512577/
https://ncbi.nlm.nih.gov/pubmed/21317894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.2018
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki