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Identification of ML251, a Potent Inhibitor of T. brucei and T. cruzi Phosphofructokinase
[Image: see text] Human African Trypanosomiasis (HAT) is a severe, often fatal disease caused by the parasitic protist Trypanosoma brucei. The glycolytic pathway has been identified as the sole mechanism for ATP generation in the infective stage of these organisms, and several glycolytic enzymes, ph...
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| Hlavní autoři: | , , , , , , , , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
American Chemical
Society
2013
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| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4027769/ https://ncbi.nlm.nih.gov/pubmed/24900769 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ml400259d |
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