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Mechanism of Mos1 transposition: insights from structural analysis

We present the crystal structure of the catalytic domain of Mos1 transposase, a member of the Tc1/mariner family of transposases. The structure comprises an RNase H-like core, bringing together an aspartic acid triad to form the active site, capped by N- and C-terminal α-helices. We have solved stru...

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Autors principals: Richardson, Julia M, Dawson, Angela, O'hagan, Natasha, Taylor, Paul, Finnegan, David J, Walkinshaw, Malcolm D
Format: Artigo
Idioma:Inglês
Publicat: 2006
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1422158/
https://ncbi.nlm.nih.gov/pubmed/16511570
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601018
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