Multidrug binding properties of the AcrB efflux pump characterized by molecular dynamics simulations

por Vargiu, Attilio V., Nikaido, Hiroshi
Publicado 2012

Some Ligands Enhance the Efflux of Other Ligands by the Escherichia coli Multidrug Pump AcrB

por Kinana, Alfred D., Vargiu, Attilio V., Nikaido, Hiroshi
Publicado 2013

Effect of site-directed mutations in multidrug efflux pump AcrB examined by quantitative efflux assays

por Kinana, Alfred D., Vargiu, Attilio V., Nikaido, Hiroshi
Publicado en Biochem Biophys Res Commun (2016)

The Phe-Phe Motif for Peptide Self-Assembly in Nanomedicine

por Marchesan, Silvia, Vargiu, Attilio V., Styan, Katie E.
Publicado en Molecules (2015)

Sliding of Alkylating Anticancer Drugs along the Minor Groove of DNA: New Insights on Sequence Selectivity

por Vargiu, Attilio V., Ruggerone, Paolo, Magistrato, Alessandra, Carloni, Paolo
Publicado 2008

Computational Study of Correlated Domain Motions in the AcrB Efflux Transporter

por Schulz, Robert, Vargiu, Attilio V., Ruggerone, Paolo, Kleinekathöfer, Ulrich
Publicado en Biomed Res Int (2015)

Aminoacyl β-naphthylamides as substrates and modulators of AcrB multidrug efflux pump

por Kinana, Alfred D., Vargiu, Attilio V., May, Thithiwat, Nikaido, Hiroshi
Publicado en Proc Natl Acad Sci U S A (2016)

Editorial: Bad Bugs in the XXIst Century: Resistance Mediated by Multi-Drug Efflux Pumps in Gram-Negative Bacteria

por Vargiu, Attilio V., Pos, Klaas M., Poole, Keith, Nikaido, Hiroshi
Publicado en Front Microbiol (2016)

Functional Rotation of the Transporter AcrB: Insights into Drug Extrusion from Simulations

por Schulz, Robert, Vargiu, Attilio V., Collu, Francesca, Kleinekathöfer, Ulrich, Ruggerone, Paolo
Publicado 2010

Molecular Dynamics Computer Simulations of Multidrug RND Efflux Pumps

por Ruggerone, Paolo, Vargiu, Attilio V., Collu, Francesca, Fischer, Nadine, Kandt, Christian
Publicado 2013

Molecular Mechanism of MBX2319 Inhibition of Escherichia coli AcrB Multidrug Efflux Pump and Comparison with Other Inhibitors

por Vargiu, Attilio V., Ruggerone, Paolo, Opperman, Timothy J., Nguyen, Son T., Nikaido, Hiroshi
Publicado 2014

Molecular Rationale behind the Differential Substrate Specificity of Bacterial RND Multi-Drug Transporters

por Ramaswamy, Venkata Krishnan, Vargiu, Attilio V., Malloci, Giuliano, Dreier, Jürg, Ruggerone, Paolo
Publicado en Sci Rep (2017)

Molecular Determinants of the Promiscuity of MexB and MexY Multidrug Transporters of Pseudomonas aeruginosa

por Ramaswamy, Venkata K., Vargiu, Attilio V., Malloci, Giuliano, Dreier, Jürg, Ruggerone, Paolo
Publicado en Front Microbiol (2018)

Molecular Interactions of Cephalosporins with the Deep Binding Pocket of the RND Transporter AcrB

por Atzori, Alessio, Malloci, Giuliano, Prajapati, Jigneshkumar Dahyabhai, Basciu, Andrea, Bosin, Andrea, Kleinekathöfer, Ulrich, Dreier, Jürg, Vargiu, Attilio V., Ruggerone, Paolo
Publicado en J Phys Chem B (2019)

Binding and transport of carboxylated drugs by the multidrug transporter AcrB

por Tam, Heng-Keat, Malviya, Viveka N., Foong, Wuen-Ee, Herrmann, Andrea, Malloci, Giuliano, Ruggerone, Paolo, Vargiu, Attilio V., Pos, Klaas M.
Publicado en J Mol Biol (2019)

Relevance of Ebola virus VP35 homo-dimerization on the type I interferon cascade inhibition

por Di Palma, Francesco, Daino, Gian Luca, Ramaswamy, Venkata Krishnan, Corona, Angela, Frau, Aldo, Fanunza, Elisa, Vargiu, Attilio V, Tramontano, Enzo, Ruggerone, Paolo
Publicado en Antivir Chem Chemother (2019)

A Novel Dendrimeric Peptide with Antimicrobial Properties: Structure-Function Analysis of SB056

por Scorciapino, Mariano A., Pirri, Giovanna, Vargiu, Attilio V., Ruggerone, Paolo, Giuliani, Andrea, Casu, Mariano, Buerck, Jochen, Wadhwani, Parvesh, Ulrich, Anne S., Rinaldi, Andrea C.
Publicado 2012

Nanoscale Assembly of Functional Peptides with Divergent Programming Elements

por Garcia, Ana M., Melchionna, Michele, Bellotto, Ottavia, Kralj, Slavko, Semeraro, Sabrina, Parisi, Evelina, Iglesias, Daniel, D’Andrea, Paola, De Zorzi, Rita, Vargiu, Attilio V., Marchesan, Silvia
Publicado en ACS Nano (2021)

Heterochirality and Halogenation Control Phe-Phe Hierarchical Assembly

por Kralj, Slavko, Bellotto, Ottavia, Parisi, Evelina, Garcia, Ana M., Iglesias, Daniel, Semeraro, Sabrina, Deganutti, Caterina, D’Andrea, Paola, Vargiu, Attilio V., Geremia, Silvano, De Zorzi, Rita, Marchesan, Silvia
Publicado en ACS Nano (2020)

Chlorpromazine and Amitriptyline Are Substrates and Inhibitors of the AcrB Multidrug Efflux Pump

por Grimsey, Elizabeth M., Fais, Chiara, Marshall, Robert L., Ricci, Vito, Ciusa, Maria Laura, Stone, Jack W., Ivens, Alasdair, Malloci, Giuliano, Ruggerone, Paolo, Vargiu, Attilio V., Piddock, Laura J. V.
Publicado en mBio (2020)