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Relevance of Ebola virus VP35 homo-dimerization on the type I interferon cascade inhibition
Ebola virus high lethality relies on its ability to efficiently bypass the host innate antiviral response, which senses the viral dsRNA through the RIG-I receptor and induces type I interferon α/β production. In the bypassing action, the Ebola virus protein VP35 plays a pivotal role at multiple leve...
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| Publicado no: | Antivir Chem Chemother |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
SAGE Publications
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6883671/ https://ncbi.nlm.nih.gov/pubmed/31744306 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/2040206619889220 |
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