Intracellular human antibody fragments recognizing the VP35 protein of Zaire Ebola filovirus inhibit the protein activity

BACKGROUND: Ebola hemorrhagic fever is caused by the Ebola filovirus (EBOV), which is one of the most aggressive infectious agents known worldwide. The EBOV pathogenesis starts with uncontrolled viral replication and subversion of both the innate and adaptive host immune response. The multifunctiona...

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Publicat a:BMC Biotechnol
Autors principals: Flego, Michela, Frau, Aldo, Accardi, Luisa, Mallano, Alessandra, Ascione, Alessandro, Gellini, Mara, Fanunza, Elisa, Vella, Stefano, Di Bonito, Paola, Tramontano, Enzo
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2019
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6727353/
https://ncbi.nlm.nih.gov/pubmed/31488108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12896-019-0554-2
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