Intracellular human antibody fragments recognizing the VP35 protein of Zaire Ebola filovirus inhibit the protein activity

BACKGROUND: Ebola hemorrhagic fever is caused by the Ebola filovirus (EBOV), which is one of the most aggressive infectious agents known worldwide. The EBOV pathogenesis starts with uncontrolled viral replication and subversion of both the innate and adaptive host immune response. The multifunctiona...

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Detalhes bibliográficos
Publicado no:BMC Biotechnol
Main Authors: Flego, Michela, Frau, Aldo, Accardi, Luisa, Mallano, Alessandra, Ascione, Alessandro, Gellini, Mara, Fanunza, Elisa, Vella, Stefano, Di Bonito, Paola, Tramontano, Enzo
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6727353/
https://ncbi.nlm.nih.gov/pubmed/31488108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12896-019-0554-2
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