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Molecular Interactions of Cephalosporins with the Deep Binding Pocket of the RND Transporter AcrB

The drug/proton antiporter AcrB, part of the major efflux pump AcrABZ-TolC in Escherichia coli, is characterized by its impressive ability to transport chemically diverse compounds, conferring a multidrug resistance phenotype. However, the molecular features differentiating between good and poor sub...

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Detalhes bibliográficos
Publicado no:J Phys Chem B
Main Authors: Atzori, Alessio, Malloci, Giuliano, Prajapati, Jigneshkumar Dahyabhai, Basciu, Andrea, Bosin, Andrea, Kleinekathöfer, Ulrich, Dreier, Jürg, Vargiu, Attilio V., Ruggerone, Paolo
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6939625/
https://ncbi.nlm.nih.gov/pubmed/31070373
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jpcb.9b01351
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