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Molecular Interactions of Carbapenem Antibiotics with the Multidrug Efflux Transporter AcrB of Escherichia coli

The drug/proton antiporter AcrB, engine of the major efflux pump AcrAB(Z)-TolC of Escherichia coli and other bacteria, is characterized by its impressive ability to transport chemically diverse compounds, conferring a multi-drug resistance (MDR) phenotype. Although hundreds of small molecules are kn...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Atzori, Alessio, Malloci, Giuliano, Cardamone, Francesca, Bosin, Andrea, Vargiu, Attilio Vittorio, Ruggerone, Paolo
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7037162/
https://ncbi.nlm.nih.gov/pubmed/32013182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21030860
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