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Some Ligands Enhance the Efflux of Other Ligands by the Escherichia coli Multidrug Pump AcrB

By measuring quantitatively the active efflux of cephalosporins by an RND (resistance-nodulation-division) family efflux pump AcrB in intact cells of Escherichia coli, we found that the simultaneous presence of another substrate, such as chloramphenicol, benzene, cyclohexane, or Arg β-naphthilamide...

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Bibliographic Details
Main Authors: Kinana, Alfred D., Vargiu, Attilio V., Nikaido, Hiroshi
Format: Artigo
Language:Inglês
Published: 2013
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3951271/
https://ncbi.nlm.nih.gov/pubmed/24205856
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi401303v
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