Picky nascent peptides do not talk to foreign ribosomes

Por Vázquez-Laslop, Nora, Mankin, Alexander S.
Publicado em 2011

Protein accounting in the cellular economy

Por Vázquez-Laslop, Nora, Mankin, Alexander S.
Publicado em 2014

Increased Persistence in Escherichia coli Caused by Controlled Expression of Toxins or Other Unrelated Proteins

Por Vázquez-Laslop, Nora, Lee, Hyunwoo, Neyfakh, Alexander A.
Publicado em 2006

Regulation of gene expression by macrolide-induced ribosomal frameshifting

Por Gupta, Pulkit, Kannan, Krishna, Mankin, Alexander S., Vázquez-Laslop, Nora
Publicado em 2013

Molecular Sieve Mechanism of Selective Release of Cytoplasmic Proteins by Osmotically Shocked Escherichia coli

Por Vázquez-Laslop, Nora, Lee, Hyunwoo, Hu, Rong, Neyfakh, Alex A.
Publicado em 2001

Isolation of Antibiotic Hypersusceptibility Mutants of Acinetobacter spp. by Selection for DNA Release

Por Lee, Hyunwoo, Vázquez-Laslop, Nora, Klyachko, Katya A., Neyfakh, Alex A.
Publicado em 2003

The key function of a conserved and modified rRNA residue in the ribosomal response to the nascent peptide

Por Vázquez-Laslop, Nora, Ramu, Haripriya, Klepacki, Dorota, Kannan, Krishna, Mankin, Alexander S
Publicado em 2010

Identifying the targets of aminoacyl-tRNA synthetase inhibitors by primer extension inhibition

Por Orelle, Cédric, Szal, Teresa, Klepacki, Dorota, Shaw, Karen J., Vázquez-Laslop, Nora, Mankin, Alexander S.
Publicado em 2013

Binding of macrolide antibiotics leads to ribosomal selection against specific substrates based on their charge and size

Por Sothiselvam, Shanmugapriya, Neuner, Sandro, Rigger, Lukas, Klepacki, Dorota, Micura, Ronald, Vázquez-Laslop, Nora, Mankin, Alexander S.
Publicado no Cell Rep (2016)

Role of antibiotic ligand in nascent peptide-dependent ribosome stalling

Por Vázquez-Laslop, Nora, Klepacki, Dorota, Mulhearn, Debbie C., Ramu, Haripriya, Krasnykh, Olga, Franzblau, Scott, Mankin, Alexander S.
Publicado em 2011

Drug-Sensing by the Ribosome Induces Translational Arrest via Active Site Perturbation

Por Arenz, Stefan, Meydan, Sezen, Starosta, Agata L., Berninghausen, Otto, Beckmann, Roland, Vázquez-Laslop, Nora, Wilson, Daniel N.
Publicado no Mol Cell (2014)

Structures of BmrR-Drug Complexes Reveal a Rigid Multidrug Binding Pocket and Transcription Activation through Tyrosine Expulsion

Por Newberry, Kate J., Huffman, Joy L., Miller, Marshall C., Vazquez-Laslop, Nora, Neyfakh, Alex A., Brennan, Richard G.
Publicado em 2008

Molecular basis for erythromycin-dependent ribosome-stalling during translation of the ErmBL leader peptide

Por Arenz, Stefan, Ramu, Haripriya, Gupta, Pulkit, Berninghausen, Otto, Beckmann, Roland, Vázquez-Laslop, Nora, Mankin, Alexander S., Wilson, Daniel N.
Publicado em 2014

Context-specific inhibition of translation by ribosomal antibiotics targeting the peptidyl transferase center

Por Marks, James, Kannan, Krishna, Roncase, Emily J., Klepacki, Dorota, Kefi, Amira, Orelle, Cédric, Vázquez-Laslop, Nora, Mankin, Alexander S.
Publicado no Proc Natl Acad Sci U S A (2016)

Negamycin interferes with decoding and translocation by simultaneous interaction with rRNA and tRNA

Por Polikanov, Yury S., Szal, Teresa, Jiang, Fuyan, Gupta, Pulkit, Matsuda, Ryoichi, Shiozuka, Masataka, Steitz, Thomas A., Vázquez-Laslop, Nora, Mankin, Alexander S.
Publicado no Mol Cell (2014)

Resistance to ketolide antibiotics by coordinated expression of rRNA methyltransferases in a bacterial producer of natural ketolides

Por Almutairi, Mashal M., Park, Sung Ryeol, Rose, Simon, Hansen, Douglas A., Vázquez-Laslop, Nora, Douthwaite, Stephen, Sherman, David H., Mankin, Alexander S.
Publicado no Proc Natl Acad Sci U S A (2015)

Programmed ribosomal frameshifting generates a copper transporter and a copper chaperone from the same gene

Por Meydan, Sezen, Klepacki, Dorota, Karthikeyan, Subbulakshmi, Margus, Tõnu, Thomas, Paul, Jones, John E., Khan, Yousuf, Briggs, Joseph, Dinman, Jonathan D., Vázquez-Laslop, Nora, Mankin, Alexander S.
Publicado no Mol Cell (2017)

Macrolide antibiotics allosterically predispose the ribosome for translation arrest

Por Sothiselvam, Shanmugapriya, Liu, Bo, Han, Wei, Ramu, Haripriya, Klepacki, Dorota, Atkinson, Gemma Catherine, Brauer, Age, Remm, Maido, Tenson, Tanel, Schulten, Klaus, Vázquez-Laslop, Nora, Mankin, Alexander S.
Publicado em 2014

Interactions of the TnaC nascent peptide with rRNA in the exit tunnel enable the ribosome to respond to free tryptophan

Por Martínez, Allyson K., Gordon, Emily, Sengupta, Arnab, Shirole, Nitin, Klepacki, Dorota, Martinez-Garriga, Blanca, Brown, Lewis M., Benedik, Michael J., Yanofsky, Charles, Mankin, Alexander S., Vazquez-Laslop, Nora, Sachs, Matthew S., Cruz-Vera, Luis R.
Publicado em 2014