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Role of antibiotic ligand in nascent peptide-dependent ribosome stalling

Specific nascent peptides in the ribosome exit tunnel can elicit translation arrest. Such ribosome stalling is used for regulation of expression of some bacterial and eukaryotic genes. The stalling is sensitive to additional cellular cues, most commonly the binding of specific small-molecular-weight...

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Main Authors: Vázquez-Laslop, Nora, Klepacki, Dorota, Mulhearn, Debbie C., Ramu, Haripriya, Krasnykh, Olga, Franzblau, Scott, Mankin, Alexander S.
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2011
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3127923/
https://ncbi.nlm.nih.gov/pubmed/21670252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1103474108
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