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Role of antibiotic ligand in nascent peptide-dependent ribosome stalling

Specific nascent peptides in the ribosome exit tunnel can elicit translation arrest. Such ribosome stalling is used for regulation of expression of some bacterial and eukaryotic genes. The stalling is sensitive to additional cellular cues, most commonly the binding of specific small-molecular-weight...

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Detalhes bibliográficos
Main Authors: Vázquez-Laslop, Nora, Klepacki, Dorota, Mulhearn, Debbie C., Ramu, Haripriya, Krasnykh, Olga, Franzblau, Scott, Mankin, Alexander S.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3127923/
https://ncbi.nlm.nih.gov/pubmed/21670252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1103474108
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