Macrolide antibiotics allosterically predispose the ribosome for translation arrest

Translation arrest directed by nascent peptides and small cofactors controls expression of important bacterial and eukaryotic genes, including antibiotic resistance genes, activated by binding of macrolide drugs to the ribosome. Previous studies suggested that specific interactions between the nasce...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Sothiselvam, Shanmugapriya, Liu, Bo, Han, Wei, Ramu, Haripriya, Klepacki, Dorota, Atkinson, Gemma Catherine, Brauer, Age, Remm, Maido, Tenson, Tanel, Schulten, Klaus, Vázquez-Laslop, Nora, Mankin, Alexander S.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences 2014
Pynciau:
Biological Sciences
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4103360/
https://ncbi.nlm.nih.gov/pubmed/24961372
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1403586111
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