Macrolide antibiotics allosterically predispose the ribosome for translation arrest

Translation arrest directed by nascent peptides and small cofactors controls expression of important bacterial and eukaryotic genes, including antibiotic resistance genes, activated by binding of macrolide drugs to the ribosome. Previous studies suggested that specific interactions between the nasce...

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מידע ביבליוגרפי
Main Authors: Sothiselvam, Shanmugapriya, Liu, Bo, Han, Wei, Ramu, Haripriya, Klepacki, Dorota, Atkinson, Gemma Catherine, Brauer, Age, Remm, Maido, Tenson, Tanel, Schulten, Klaus, Vázquez-Laslop, Nora, Mankin, Alexander S.
פורמט: Artigo
שפה:Inglês
יצא לאור: National Academy of Sciences 2014
נושאים:
Biological Sciences
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC4103360/
https://ncbi.nlm.nih.gov/pubmed/24961372
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1403586111
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