IFNA2: The prototypic human alpha interferon

Por Paul, Franciane, Pellegrini, Sandra, Uzé, Gilles
Publicado no Gene (2015)

A dual role for the kinase-like domain of the tyrosine kinase Tyk2 in interferon-α signaling

Por Yeh, Tammie C., Dondi, Elisabetta, Uzé, Gilles, Pellegrini, Sandra
Publicado em 2000

Comparative Genomic Analysis of the Interferon/Interleukin-10 Receptor Gene Cluster

Por Reboul, Jérôme, Gardiner, Katheleen, Monneron, Danièle, Uzé, Gilles, Lutfalla, Georges
Publicado em 1999

Receptor Density Is Key to the Alpha2/Beta Interferon Differential Activities

Por Moraga, Ignacio, Harari, Daniel, Schreiber, Gideon, Uzé, Gilles, Pellegrini, Sandra
Publicado em 2009

Comparable potency of IFNα2 and IFNβ on immediate JAK/STAT activation but differential down-regulation of IFNAR2

Por Marijanovic, Zrinka, Ragimbeau, Josiane, vanderHeyden, José, Uzé, Gilles, Pellegrini, Sandra
Publicado em 2007

The tyrosine kinase Tyk2 controls IFNAR1 cell surface expression

Por Ragimbeau, Josiane, Dondi, Elisabetta, Alcover, Andrés, Eid, Pierre, Uzé, Gilles, Pellegrini, Sandra
Publicado em 2003

Harnessing Mechanistic Knowledge on Beneficial Versus Deleterious IFN-I Effects to Design Innovative Immunotherapies Targeting Cytokine Activity to Specific Cell Types

Por Tomasello, Elena, Pollet, Emeline, Vu Manh, Thien-Phong, Uzé, Gilles, Dalod, Marc
Publicado em 2014

Assessment of mTOR-Dependent Translational Regulation of Interferon Stimulated Genes

Por Livingstone, Mark, Sikström, Kristina, Robert, Philippe A., Uzé, Gilles, Larsson, Ola, Pellegrini, Sandra
Publicado no PLoS One (2015)

The amino-terminal region of Tyk2 sustains the level of interferon α receptor 1, a component of the interferon α/β receptor

Por Gauzzi, M. Cristina, Barbieri, Giovanna, Richter, Marc F., Uzé, Gilles, Ling, Leona, Fellous, Marc, Pellegrini, Sandra
Publicado em 1997

The GTP/GDP Cycling of Rho GTPase TCL Is an Essential Regulator of the Early Endocytic Pathway

Por de Toledo, Marion, Senic-Matuglia, Francesca, Salamero, Jean, Uze, Gilles, Comunale, Franck, Fort, Philippe, Blangy, Anne
Publicado em 2003

Differential Activity of Type I Interferon Subtypes for Dendritic Cell Differentiation

Por Garcin, Geneviève, Bordat, Yann, Chuchana, Paul, Monneron, Danièle, Law, Helen K. W., Piehler, Jacob, Uzé, Gilles
Publicado em 2013

Interferon-α and -β differentially regulate osteoclastogenesis: Role of differential induction of chemokine CXCL11 expression

Por Coelho, Luiz F. Leomil, de Freitas Almeida, Gabriel Magno, Mennechet, Franck J. D., Blangy, Anne, Uzé, Gilles
Publicado em 2005

Inquiring into the Differential Action of Interferons (IFNs): an IFN-α2 Mutant with Enhanced Affinity to IFNAR1 Is Functionally Similar to IFN-β

Por Jaitin, Diego A., Roisman, Laila C., Jaks, Eva, Gavutis, Martynas, Piehler, Jacob, Van der Heyden, Jose, Uze, Gilles, Schreiber, Gideon
Publicado em 2006

USP18-Based Negative Feedback Control Is Induced by Type I and Type III Interferons and Specifically Inactivates Interferon α Response

Por François-Newton, Véronique, Magno de Freitas Almeida, Gabriel, Payelle-Brogard, Béatrice, Monneron, Danièle, Pichard-Garcia, Lydiane, Piehler, Jacob, Pellegrini, Sandra, Uzé, Gilles
Publicado em 2011

IFNα signaling through PKC-θ is essential for antitumor NK cell function

Por Comet, Natalia R, Aguiló, Juan Ignacio, Rathoré, Moeez G, Catalán, Elena, Garaude, Johan, Uzé, Gilles, Naval, Javier, Pardo, Julián, Villalba, Martín, Anel, Alberto
Publicado no Oncoimmunology (2014)

Tumor Necrosis Factor Alpha Enhances Influenza A Virus-Induced Expression of Antiviral Cytokines by Activating RIG-I Gene Expression

Por Matikainen, Sampsa, Sirén, Jukka, Tissari, Jorma, Veckman, Ville, Pirhonen, Jaana, Severa, Martina, Sun, Qiang, Lin, Rongtuan, Meri, Seppo, Uzé, Gilles, Hiscott, John, Julkunen, Ilkka
Publicado em 2006

Transcriptional profiles discriminate bone marrow-derived and synovium-derived mesenchymal stem cells

Por Djouad, Farida, Bony, Claire, Häupl, Thomas, Uzé, Gilles, Lahlou, Najiba, Louis-Plence, Pascale, Apparailly, Florence, Canovas, François, Rème, Thierry, Sany, Jacques, Jorgensen, Christian, Noël, Danièle
Publicado em 2005

Receptor dimerization dynamics as a regulatory valve for plasticity of type I interferon signaling

Por Wilmes, Stephan, Beutel, Oliver, Li, Zhi, Francois-Newton, Véronique, Richter, Christian P., Janning, Dennis, Kroll, Cindy, Hanhart, Patrizia, Hötte, Katharina, You, Changjiang, Uzé, Gilles, Pellegrini, Sandra, Piehler, Jacob
Publicado no J Cell Biol (2015)

A safe and highly efficient tumor-targeted type I interferon immunotherapy depends on the tumor microenvironment

Por Cauwels, Anje, Van Lint, Sandra, Garcin, Geneviève, Bultinck, Jennyfer, Paul, Franciane, Gerlo, Sarah, Van der Heyden, José, Bordat, Yann, Catteeuw, Dominiek, De Cauwer, Lode, Rogge, Elke, Verhee, Annick, Uzé, Gilles, Tavernier, Jan
Publicado no Oncoimmunology (2017)

Human intracellular ISG15 prevents interferon-α/β over-amplification and auto-inflammation

Por Zhang, Xianqin, Bogunovic, Dusan, Payelle-Brogard, Béatrice, Francois-Newton, Véronique, Speer, Scott D., Yuan, Chao, Volpi, Stefano, Li, Zhi, Sanal, Ozden, Mansouri, Davood, Tezcan, Ilhan, Rice, Gillian I., Chen, Chunyuan, Mansouri, Nahal, Alireza Mahdaviani, Seyed, Itan, Yuval, Boisson, Bertrand, Okada, Satoshi, Zeng, Lu, Wang, Xing, Jiang, Hui, Liu, Wenqiang, Han, Tiantian, Liu, Delin, Ma, Tao, Wang, Bo, Liu, Mugen, Liu, Jing-Yu, Wang, Qing K., Yalnizoglu, Dilek, Radoshevich, Lilliana, Uzé, Gilles, Gros, Philippe, Rozenberg, Flore, Zhang, Shen-Ying, Jouanguy, Emmanuelle, Bustamante, Jacinta, Garcìa-Sastre, Adolfo, Abel, Laurent, Lebon, Pierre, Notarangelo, Luigi D., Crow, Yanick J., Boisson-Dupuis, Stèphanie, Casanova, Jean-Laurent, Pellegrini, Sandra
Publicado no Nature (2014)