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Receptor Density Is Key to the Alpha2/Beta Interferon Differential Activities
Multiple type I interferons (IFN-α/β) elicit Jak/Stat activation, rapid gene induction, and pleiotropic effects, such as differentiation, antiviral protection, and blocks in proliferation, which are dependent on the IFN subtype and the cellular context. To date, ligand- and receptor-specific molecul...
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Main Authors: | , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
American Society for Microbiology (ASM)
2009
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2725717/ https://ncbi.nlm.nih.gov/pubmed/19564411 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01808-08 |
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