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Receptor Density Is Key to the Alpha2/Beta Interferon Differential Activities

Multiple type I interferons (IFN-α/β) elicit Jak/Stat activation, rapid gene induction, and pleiotropic effects, such as differentiation, antiviral protection, and blocks in proliferation, which are dependent on the IFN subtype and the cellular context. To date, ligand- and receptor-specific molecul...

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Detalhes bibliográficos
Main Authors: Moraga, Ignacio, Harari, Daniel, Schreiber, Gideon, Uzé, Gilles, Pellegrini, Sandra
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2725717/
https://ncbi.nlm.nih.gov/pubmed/19564411
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01808-08
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