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Stochastic Receptor Expression Determines Cell Fate upon Interferon Treatment

Type I interferons trigger diverse biological effects by binding a common receptor, composed of IFNAR1 and IFNAR2. Intriguingly, while the activation of an antiviral state is common to all cells, antiproliferative activity and apoptosis affect only part of the population, even when cells are stimula...

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Detalhes bibliográficos
Main Authors: Levin, Doron, Harari, Daniel, Schreiber, Gideon
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3147786/
https://ncbi.nlm.nih.gov/pubmed/21690295
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.05251-11
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