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Engineering of regulated stochastic cell fate determination

Both microbes and multicellular organisms actively regulate their cell fate determination to cope with changing environments or to ensure proper development. Here, we use synthetic biology approaches to engineer bistable gene networks to demonstrate that stochastic and permanent cell fate determinat...

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Autori principali: Wu, Min, Su, Ri-Qi, Li, Xiaohui, Ellis, Tom, Lai, Ying-Cheng, Wang, Xiao
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3696818/
https://ncbi.nlm.nih.gov/pubmed/23754391
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1305423110
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