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MicroRNA-based regulation of epithelial–hybrid–mesenchymal fate determination

Forward and backward transitions between epithelial and mesenchymal phenotypes play crucial roles in embryonic development and tissue repair. Aberrantly regulated transitions are also a hallmark of cancer metastasis. The genetic network that regulates these transitions appears to allow for the exist...

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Autori principali: Lu, Mingyang, Jolly, Mohit Kumar, Levine, Herbert, Onuchic, José N., Ben-Jacob, Eshel
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3831488/
https://ncbi.nlm.nih.gov/pubmed/24154725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1318192110
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