Towards elucidating the connection between epithelial–mesenchymal transitions and stemness

Epithelial cells undergoing epithelial-to-mesenchymal transitions have often been shown to behave as cancer stem cells, but the precise molecular connection remains elusive. At the genetic level, stemness is governed by LIN28/let-7 double inhibition switch, whereas EMT/MET is controlled by miR-200/Z...

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Библиографические подробности
Опубликовано в: :J R Soc Interface
Главные авторы: Jolly, Mohit Kumar, Huang, Bin, Lu, Mingyang, Mani, Sendurai A., Levine, Herbert, Ben-Jacob, Eshel
Формат: Artigo
Язык:Inglês
Опубликовано: The Royal Society 2014
Предметы:
Research Articles
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4223923/
https://ncbi.nlm.nih.gov/pubmed/25339690
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsif.2014.0962
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