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A possible role for epigenetic feedback regulation in the dynamics of the Epithelial-Mesenchymal Transition (EMT)

The epithelial-mesenchymal transition (EMT) often plays a critical role in cancer metastasis and chemoresistance, and decoding its dynamics is crucial to design effective therapeutics. EMT is regulated at multiple levels – transcriptional, translational, protein stability, and epigenetics; the mecha...

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Detalhes bibliográficos
Publicado no:Phys Biol
Main Authors: Jia, Wen, Deshmukh, Abhijeet, Mani, Sendurai A., Jolly, Mohit Kumar, Levine, Herbert
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7085921/
https://ncbi.nlm.nih.gov/pubmed/31342918
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1088/1478-3975/ab34df
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