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A Theoretical Approach to Coupling the Epithelial-Mesenchymal Transition (EMT) to Extracellular Matrix (ECM) Stiffness via LOXL2

SIMPLE SUMMARY: Epithelial-mesenchymal transition (EMT) is a key process in cancer progression through which cells weaken their cell-cell adhesion and gain mobility and invasive traits. Besides chemical signaling, recent studies have established the connection of EMT to mechanical microenvironment,...

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Detalhes bibliográficos
Publicado no:Cancers (Basel)
Main Authors: Deng, Youyuan, Chakraborty, Priyanka, Jolly, Mohit Kumar, Levine, Herbert
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8037024/
https://ncbi.nlm.nih.gov/pubmed/33807227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers13071609
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