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A mechanism for epithelial-mesenchymal heterogeneity in a population of cancer cells

Epithelial-mesenchymal heterogeneity implies that cells within the same tumor can exhibit different phenotypes—epithelial, mesenchymal, or one or more hybrid epithelial-mesenchymal phenotypes. This behavior has been reported across cancer types, both in vitro and in vivo, and implicated in multiple...

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Veröffentlicht in:PLoS Comput Biol
Hauptverfasser: Tripathi, Shubham, Chakraborty, Priyanka, Levine, Herbert, Jolly, Mohit Kumar
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2020
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7034928/
https://ncbi.nlm.nih.gov/pubmed/32040502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1007619
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