Epigenetic feedback and stochastic partitioning during cell division can drive resistance to EMT

Epithelial-mesenchymal transition (EMT) and its reverse process mesenchymal-epithelial transition (MET) are central to metastatic aggressiveness and therapy resistance in solid tumors. While molecular determinants of both processes have been extensively characterized, the heterogeneity in the respon...

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Vydáno v:Oncotarget
Hlavní autoři: Jia, Wen, Tripathi, Shubham, Chakraborty, Priyanka, Chedere, Adithya, Rangarajan, Annapoorni, Levine, Herbert, Jolly, Mohit Kumar
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2020
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7343638/
https://ncbi.nlm.nih.gov/pubmed/32676163
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.27651
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