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Multi-Stability and Consequent Phenotypic Plasticity in AMPK-Akt Double Negative Feedback Loop in Cancer Cells

Adaptation and survival of cancer cells to various stress and growth factor conditions is crucial for successful metastasis. A double-negative feedback loop between two serine/threonine kinases AMPK (AMP-activated protein kinase) and Akt can regulate the adaptation of breast cancer cells to matrix-d...

詳細記述

保存先:
書誌詳細
出版年:J Clin Med
主要な著者: Chedere, Adithya, Hari, Kishore, Kumar, Saurav, Rangarajan, Annapoorni, Jolly, Mohit Kumar
フォーマット: Artigo
言語:Inglês
出版事項: MDPI 2021
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7865639/
https://ncbi.nlm.nih.gov/pubmed/33530625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/jcm10030472
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