AMPK–Akt Double-Negative Feedback Loop in Breast Cancer Cells Regulates Their Adaptation to Matrix Deprivation

Cell detachment from the extracellular matrix triggers anoikis. Disseminated tumor cells must adapt to survive matrix deprivation, while still retaining the ability to attach at secondary sites and reinitiate cell division. In this study, we elucidate mechanisms that enable reversible matrix attachm...

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Publicado en:Cancer Res
Main Authors: Saha, Manipa, Kumar, Saurav, Bukhari, Shoiab, Balaji, Sai A., Kumar, Prashant, Hindupur, Sravanth K., Rangarajan, Annapoorni
Formato: Artigo
Idioma:Inglês
Publicado: 2018
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6033311/
https://ncbi.nlm.nih.gov/pubmed/29339542
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-17-2090
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