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AMP-activated protein kinase promotes epithelial-mesenchymal transition in cancer cells through Twist1 upregulation

The developmental programme of epithelial-mesenchymal transition (EMT), involving loss of epithelial and acquisition of mesenchymal properties, plays an important role in the invasion-metastasis cascade of cancer cells. In the present study, we show that activation of AMP-activated protein kinase (A...

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Dettagli Bibliografici
Pubblicato in:J Cell Sci
Autori principali: Saxena, Meera, Balaji, Sai A., Deshpande, Neha, Ranganathan, Santhalakshmi, Pillai, Divya Mohan, Hindupur, Sravanth Kumar, Rangarajan, Annapoorni
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Company of Biologists Ltd 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6080604/
https://ncbi.nlm.nih.gov/pubmed/29950484
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.208314
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