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Simian Virus 40 Small T Antigen Activates AMPK and Triggers Autophagy To Protect Cancer Cells from Nutrient Deprivation

As tumors grow larger, they often experience an insufficient supply of oxygen and nutrients. Hence, cancer cells must develop mechanisms to overcome these stresses. Using an in vitro transformation model where the presence of the simian virus 40 (SV40) small T (ST) antigen has been shown to be criti...

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Autors principals: Kumar, Sravanth Hindupur, Rangarajan, Annapoorni
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 2009
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2738183/
https://ncbi.nlm.nih.gov/pubmed/19515765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00603-09
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