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Intestinal Dysplasia Induced by Simian Virus 40 T Antigen Is Independent of p53
Transgenic mice expressing simian virus 40 large T antigen in enterocytes develop intestinal hyperplasia that progresses to dysplasia with age. Hyperplasia is dependent on T antigen binding to the retinoblastoma (pRb) family of tumor suppressor proteins. Mice expressing a truncated T antigen that in...
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| Autores principales: | , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
American Society for Microbiology
2005
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1143657/ https://ncbi.nlm.nih.gov/pubmed/15919904 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.12.7492-7502.2005 |
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