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Two Independent Regions of Simian Virus 40 T Antigen Increase CBP/p300 Levels, Alter Patterns of Cellular Histone Acetylation, and Immortalize Primary Cells

Simian virus 40 (SV40) large T antigen (SVT) interferes with normal cell regulation and thus has been used to identify cellular components controlling proliferation and homeostasis. We have previously shown that SVT-mediated transformation requires interaction with the histone acetyltransferases (HA...

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Detalhes bibliográficos
Main Authors: Sáenz Robles, Maria Teresa, Shivalila, Chikdu, Wano, Jeremy, Sorrells, Shelly, Roos, Alison, Pipas, James M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3838271/
https://ncbi.nlm.nih.gov/pubmed/24089570
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02658-13
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