Is histone acetylation the most important physiological function for CBP and p300?

Protein lysine acetyltransferases (HATs or PATs) acetylate histones and other proteins, and are principally modeled as transcriptional coactivators. CREB binding protein (CBP, CREBBP) and its paralog p300 (EP300) constitute the KAT3 family of HATs in mammals, which has mostly unique sequence identit...

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Bibliografski detalji
Glavni autori: Bedford, David C., Brindle, Paul K.
Format: Artigo
Jezik:Inglês
Izdano: Impact Journals LLC 2012
Teme:
Research Perspective
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3371760/
https://ncbi.nlm.nih.gov/pubmed/22511639
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