Is histone acetylation the most important physiological function for CBP and p300?

Protein lysine acetyltransferases (HATs or PATs) acetylate histones and other proteins, and are principally modeled as transcriptional coactivators. CREB binding protein (CBP, CREBBP) and its paralog p300 (EP300) constitute the KAT3 family of HATs in mammals, which has mostly unique sequence identit...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Bedford, David C., Brindle, Paul K.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Impact Journals LLC 2012
Gaiak:
Research Perspective
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3371760/
https://ncbi.nlm.nih.gov/pubmed/22511639
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