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Target gene context influences the transcriptional requirement for the KAT3 family of CBP and p300 histone acetyltransferases

One general principle of gene regulation is that DNA-binding transcription factors modulate transcription by recruiting cofactors that modify histones and chromatin structure. A second implicit principle is that a particular cofactor is necessary at all the target genes where the cofactor is recruit...

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Autori principali: Bedford, David C., Kasper, Lawryn H., Fukuyama, Tomofusa, Brindle, Paul K.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2829352/
https://ncbi.nlm.nih.gov/pubmed/20110770
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