Conditional Knockout Mice Reveal Distinct Functions for the Global Transcriptional Coactivators CBP and p300 in T-Cell Development

The global transcriptional coactivators CREB-binding protein (CBP) and the closely related p300 interact with over 312 proteins, making them among the most heavily connected hubs in the known mammalian protein-protein interactome. It is largely uncertain, however, if these interactions are important...

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Auteurs principaux: Kasper, Lawryn H., Fukuyama, Tomofusa, Biesen, Michelle A., Boussouar, Fayçal, Tong, Caili, de Pauw, Antoine, Murray, Peter J., van Deursen, Jan M. A., Brindle, Paul K.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2006
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Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1347027/
https://ncbi.nlm.nih.gov/pubmed/16428436
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.26.3.789-809.2006
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