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CBP/p300 double null cells reveal effect of coactivator level and diversity on CREB transactivation
It remains uncertain how the DNA sequence of mammalian genes influences the transcriptional response to extracellular signals. Here, we show that the number of CREB-binding sites (CREs) affects whether the related histone acetyltransferases (HATs) CREB-binding protein (CBP) and p300 are required for...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2982758/ https://ncbi.nlm.nih.gov/pubmed/20859256 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2010.235 |
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