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Disrupting the CH1 domain structure in the acetyltransferases CBP and p300 results in lean mice with increased metabolic control
Opposing activities of acetyltransferases and deacetylases help regulate energy balance. Mice heterozygous for the acetyltransferase CREB binding protein (CBP) are lean and insulin-sensitized but how CBP regulates energy homeostasis is unclear. In one model, the main CBP interaction with the glucago...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3163393/ https://ncbi.nlm.nih.gov/pubmed/21803292 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2011.06.010 |
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