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Intestinal Hyperplasia Induced by Simian Virus 40 Large Tumor Antigen Requires E2F2
The simian virus 40 large T antigen contributes to neoplastic transformation, in part, by targeting the Rb family of tumor suppressors. There are three known Rb proteins, pRb, p130, and p107, all of which block the cell cycle by preventing the transcription of genes regulated by the E2F family of tr...
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| Main Authors: | , , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
American Society for Microbiology (ASM)
2007
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2169091/ https://ncbi.nlm.nih.gov/pubmed/17855529 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01658-07 |
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