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Simian Virus 40 Small Tumor Antigen Induces Deregulation of the Actin Cytoskeleton and Tight Junctions in Kidney Epithelial Cells

There is increasing evidence that the transforming DNA tumor virus simian virus 40 (SV40) is associated with human malignancies. SV40 small tumor antigen (small t) interacts with endogenous serine/threonine protein phosphatase 2A (PP2A) and is required for the transforming activity of SV40 in epithe...

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Detalhes bibliográficos
Main Authors: Nunbhakdi-Craig, Viyada, Craig, Leonard, Machleidt, Thomas, Sontag, Estelle
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC149746/
https://ncbi.nlm.nih.gov/pubmed/12584304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.5.2807-2818.2003
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