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E Box-Dependent Activation of Telomerase by Human Papillomavirus Type 16 E6 Does Not Require Induction of c-myc

Human papillomavirus type 16 (HPV-16) E6 activates telomerase specifically in epithelial cells. The oncogene c-myc has also been shown to activate telomerase in several cell types. Here we show that while both HPV-16 E6 and c-myc require intact E boxes to transactivate the hTERT promoter, E6 does no...

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Autors principals: Gewin, Lindy, Galloway, Denise A.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2001
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC114450/
https://ncbi.nlm.nih.gov/pubmed/11435602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.15.7198-7201.2001
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