Functional Multimerization of the Human Telomerase Reverse Transcriptase

The telomerase enzyme exists as a large complex (∼1,000 kDa) in mammals and at minimum is composed of the telomerase RNA and the catalytic subunit telomerase reverse transcriptase (TERT). In Saccharomyces cerevisiae, telomerase appears to function as an interdependent dimer or multimer in vivo (J. P...

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Autores principales: Beattie, Tara L., Zhou, Wen, Robinson, Murray O., Harrington, Lea
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2001
Materias:
DNA Dynamics and Chromosome Structure
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC87332/
https://ncbi.nlm.nih.gov/pubmed/11509658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.21.18.6151-6160.2001
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