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Functional Multimerization of the Human Telomerase Reverse Transcriptase

The telomerase enzyme exists as a large complex (∼1,000 kDa) in mammals and at minimum is composed of the telomerase RNA and the catalytic subunit telomerase reverse transcriptase (TERT). In Saccharomyces cerevisiae, telomerase appears to function as an interdependent dimer or multimer in vivo (J. P...

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Autors principals: Beattie, Tara L., Zhou, Wen, Robinson, Murray O., Harrington, Lea
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2001
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC87332/
https://ncbi.nlm.nih.gov/pubmed/11509658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.21.18.6151-6160.2001
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