Functional Multimerization of the Human Telomerase Reverse Transcriptase

The telomerase enzyme exists as a large complex (∼1,000 kDa) in mammals and at minimum is composed of the telomerase RNA and the catalytic subunit telomerase reverse transcriptase (TERT). In Saccharomyces cerevisiae, telomerase appears to function as an interdependent dimer or multimer in vivo (J. P...

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Bibliographic Details
Main Authors: Beattie, Tara L., Zhou, Wen, Robinson, Murray O., Harrington, Lea
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2001
Subjects:
DNA Dynamics and Chromosome Structure
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC87332/
https://ncbi.nlm.nih.gov/pubmed/11509658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.21.18.6151-6160.2001
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