Functional Multimerization of the Human Telomerase Reverse Transcriptase

The telomerase enzyme exists as a large complex (∼1,000 kDa) in mammals and at minimum is composed of the telomerase RNA and the catalytic subunit telomerase reverse transcriptase (TERT). In Saccharomyces cerevisiae, telomerase appears to function as an interdependent dimer or multimer in vivo (J. P...

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Detalhes bibliográficos
Main Authors: Beattie, Tara L., Zhou, Wen, Robinson, Murray O., Harrington, Lea
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2001
Assuntos:
DNA Dynamics and Chromosome Structure
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC87332/
https://ncbi.nlm.nih.gov/pubmed/11509658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.21.18.6151-6160.2001
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