Calcium-Oxidant Signaling Network Regulates AMP-activated Protein Kinase (AMPK) Activation upon Matrix Deprivation

The AMP-activated protein kinase (AMPK) has recently been implicated in anoikis resistance. However, the molecular mechanisms that activate AMPK upon matrix detachment remain unexplored. In this study, we show that AMPK activation is a rapid and sustained phenomenon upon matrix deprivation, whereas...

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Bibliographic Details
Published in:J Biol Chem
Main Authors: Sundararaman, Ananthalakshmy, Amirtham, Usha, Rangarajan, Annapoorni
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2016
Subjects:
Cell Biology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4938166/
https://ncbi.nlm.nih.gov/pubmed/27226623
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.731257
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