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Calcium-Oxidant Signaling Network Regulates AMP-activated Protein Kinase (AMPK) Activation upon Matrix Deprivation

The AMP-activated protein kinase (AMPK) has recently been implicated in anoikis resistance. However, the molecular mechanisms that activate AMPK upon matrix detachment remain unexplored. In this study, we show that AMPK activation is a rapid and sustained phenomenon upon matrix deprivation, whereas...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Sundararaman, Ananthalakshmy, Amirtham, Usha, Rangarajan, Annapoorni
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4938166/
https://ncbi.nlm.nih.gov/pubmed/27226623
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.731257
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