Activating AMP-activated protein kinase (AMPK) slows renal cystogenesis

Renal cyst development and expansion in autosomal dominant polycystic kidney disease (ADPKD) involves both fluid secretion and abnormal proliferation of cyst-lining epithelial cells. The chloride channel of the cystic fibrosis transmembrane conductance regulator (CFTR) participates in secretion of c...

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Detalhes bibliográficos
Main Authors: Takiar, Vinita, Nishio, Saori, Seo-Mayer, Patricia, King, J. Darwin, Li, Hui, Zhang, Li, Karihaloo, Anil, Hallows, Kenneth R., Somlo, Stefan, Caplan, Michael J.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2011
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3038735/
https://ncbi.nlm.nih.gov/pubmed/21262823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1011498108
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