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AMP-activated protein kinase phosphorylation of the R domain inhibits PKA stimulation of CFTR
The metabolic sensor AMP-activated protein kinase (AMPK) has emerged as an important link between cellular metabolic status and ion transport activity. We previously found that AMPK binds to and phosphorylates CFTR in vitro and inhibits PKA-dependent stimulation of CFTR channel gating in Calu-3 bron...
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| Huvudupphovsmän: | , , , , , , |
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| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
American Physiological Society
2009
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2711654/ https://ncbi.nlm.nih.gov/pubmed/19419994 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00677.2008 |
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